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Fat-Producing Stem Cells May Harbor Obesity Cure

Experiments on mice have led to the identification of stem cells that can produce fat, say researchers. Experts at The Rockefeller University in New York say that though they have yet to determine that the cells can renew themselves, transplants of the progenitor cells isolated from the fat tissue of normal mice can restore normal fat tissue in animals that are otherwise lacking it. “In obesity, there is an increase in fat cell number. The question is: what are the events that lead to that increase? You need to know how fat cell number is normally regulated to know what goes wrong in obesity. Identifying fat cell precursors is a first step toward understanding this process,” said Matthew Rodeheffer of The Rockefeller University.

Experiments on mice have led to the identification of stem cells that can produce fat, say researchers. Experts at The Rockefeller University in New York say that though they have yet to determine that the cells can renew themselves, transplants of the progenitor cells isolated from the fat tissue of normal mice can restore normal fat tissue in animals that are otherwise lacking it. “In obesity, there is an increase in fat cell number. The question is: what are the events that lead to that increase? You need to know how fat cell number is normally regulated to know what goes wrong in obesity. Identifying fat cell precursors is a first step toward understanding this process,” said Matthew Rodeheffer of The Rockefeller University.

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